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The American Society of Clinical Oncology (ASCO) has launched a new wiki site to engage the cancer community in its clinical practice guideline development process. The new site will provide oncologists, practitioners and patients with an opportunity to provide feedback or submit evidence on individual published guidelines. All information is open for viewing. However, to comment or submit new evidence, an ASCO Guidelines Wiki user account is needed. To receive your user account, please contact


Clinical Practice Guidelines   

 ASCO Guidelines are reviewed by the Clinical Practice Guidelines Committee and submitted for publication in Journal of  Clinical Oncology (JCO). To view the original guideline publications, please visit the JCO website.  



Clinical practice guidelines serve as a guide for doctors and outline appropriate methods of treatment and care.Guidelines can address specific clinical situations (disease-oriented) or use of approved medical products, procedures, or tests (modality-oriented). Using the best available evidence, ASCO expert panels identify and develop practice recommendations for specific areas of cancer care that would benefit from using practice guidelines. The criteria for selecting topics for guidelines includes significance of clinical importance; presence of variations in patterns of, or access to care; availability of suitable data; and ethical considerations.

ASCO also publishes Guideline Endorsements and Provisional Clinical Opinions (PCOs). Endorsement of guidelines will be considered in selected circumstances either upon request from peer professional organizations, or when ASCO seeks to endorse another organization’s guideline in lieu of undertaking its own guideline on the same topic. The PCO is intended to offer timely clinical direction to the ASCO membership following the publication or presentation of potentially practice-changing data from major studies. It may serve in some cases as interim direction to the membership pending the development or updating of an ASCO clinical practice guideline.

You must have an account to comment or submit evidence. Contact the Guidelines Site Administrator for assistance.

ASCO Guideline Disclaimer: The clinical practice guidelines and other guidance published herein are provided by the American Society of Clinical Oncology, Inc. (“ASCO”) to assist practitioners in clinical decision making. The information therein should not be relied upon as being complete or accurate, nor should it be considered as inclusive of all proper treatments or methods of care or as a statement of the standard of care. With the rapid development of scientific knowledge, new evidence may emerge between the time information is developed and when it is published or read. The information is not continually updated and may not reflect the most recent evidence. The information addresses only the topics specifically identified therein and is not applicable to other interventions, diseases, or stages of diseases. This information does not mandate any particular course of medical care. Further, the information is not intended to substitute for the independent professional judgment of the treating physician, as the information does not account for individual variation among patients. Recommendations reflect high, moderate or low confidence that the recommendation reflects the net effect of a given course of action.  The use of words like “must,” “must not,” “should,” and “should not” indicate that a course of action is recommended or not recommended for either most or many patients, but there is latitude for the treating physician to select other courses of action in individual cases. In all cases, the selected course of action should be considered by the treating physician in the context of treating the individual patient. Use of the information is voluntary.  ASCO provides this information on an “as is” basis, and makes no warranty, express or implied, regarding the information. ASCO specifically disclaims any warranties of merchantability or fitness for a particular use or purpose. ASCO assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of this information or for any errors or omissions.

The content on the site is for personal use only. Requests for reuse should be directed to permissions@asco.orgTerms & Conditions apply for this site.

 ©2014 American Society of Clinical Oncology (ASCO). All Rights Reserved Worldwide

Guidelines in Development

  • Androgen Deprivation Therapy of Non-Castration Resistant Prostate Cancer PCO
  • ASCO-AUA Bladder Guideline
  • Evaluation and Management of Vulnerabilities in Older Patients Undergoing Cancer Treatment
  • Interventions to Address Sexual Problems in People with Cancer Endorsement
  • Optimum Imaging Strategies for Advanced Prostate Cancer
  • Germline and Somatic Tumor Testing Gynecologic Cancers
  • Global Palliative Care
  • Hereditary Pancreatic Cancer PCO
  • Management of Small Renal Masses
  • Osteonecrosis of the Jaw
  • Osteoporosis in Adult Cancer Survivors
  • Physician-Patient Communication
  • Salivary Gland Cancer
  • Treatment of Malignant Pleural Mesothelioma
  • Endorsement: Stage II and III Colon Cancer
  • Endorsement: Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma

These guidelines are currently not available for comment. Once they have been published in JCO, ASCO Guideline Wiki users will have the opportunity to comment.

 Updates in Development

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